Research Newsroom
2024 · Annals of the Rheumatic Diseases
EULAR recommendations for the management of systemic lupus erythematosus: 2023 update
European specialists reviewed the evidence and agreed on how lupus should be treated today, including using as little steroid as possible and aiming for remission.
2024 · Cell
Xist ribonucleoproteins promote female sex-biased autoimmunity
A molecule that only exists in cells with two X chromosomes may help explain why women get autoimmune diseases far more often. This is early-stage science, not yet a treatment.
2024 · New England Journal of Medicine
CD19-targeted CAR T cells in refractory systemic autoimmune disease
Doctors reprogrammed patients' own immune cells to wipe out the cells making harmful antibodies. A small group went into remission without further drugs. Very promising, but early and only in a few people so far.
2023 · The Lancet Rheumatology
Global, regional and national burden of rheumatoid arthritis 1990-2020
A worldwide study counted how many people live with rheumatoid arthritis in every country, and showed the burden is growing as populations age.
2023 · The Lancet
Incidence, prevalence, and co-occurrence of autoimmune disorders over time and by age, sex, and socioeconomic status
Looking at 22 million health records, about 1 in 10 people had an autoimmune condition — and women were affected much more often than men.
2022 · Science
Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis
Researchers followed millions of people over years. People who caught Epstein-Barr virus (the mono virus) were far more likely to develop MS later. It does not mean everyone with EBV gets MS — almost everyone gets EBV — but it appears to be a necessary step.
2022 · Frontiers in Immunology
The gut microbiome in rheumatoid arthritis: mechanisms and therapeutic potential
Gut bacteria may influence how rheumatoid arthritis starts. The link is real but the details, and whether changing bacteria treats disease, are still being studied.
2022 · BMJ
Vitamin D and marine omega-3 fatty acid supplementation and incident autoimmune disease (VITAL)
In a large trial of older adults, taking vitamin D for five years slightly lowered the chance of developing an autoimmune disease. The effect was modest, and results may not transfer to younger people.